Antiplatelet/antithrombotic drugs?

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Sandy Carter asked a question: Antiplatelet/antithrombotic drugs?
Asked By: Sandy Carter
Date created: Sun, May 2, 2021 11:34 PM
Date updated: Wed, Jan 12, 2022 5:30 AM

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Antiplatelet drugs (antithrombotics) 1. Dr. D. K. Brahma Associate Professor Department of Pharmacology NEIGRIHMS, Shillong Antiplatelet Drugs... 2. Definition • Drugs which interfere with platelet function and are useful in prophylaxis of thromboembolic disorders –... 3. Background – Platelet ...

Antiplatelet drugs, used with warfarin reduce formation of microthrombi on artificial heart valves and the incidence of embolism. Aspirin is clearly effective but increases risk of bleeding due to warfarin. Dipyridamole does not increase bleeding risk, but incidence of thromboembolism is reduced when it is combined with an oral anticoagulant.

Available Drugs Aspirin and Dipyridamole P2Y12 Receptor Blockers: Ticlodipine, Clopidogrel and Prasugrel GPIIb/IIIa Antagonists: Abciximab, Eptifibatide andTirofiban TXA2 synthesis inhibitor: Low dose aspirin Phosphodiesterase inhibitor: Dipyridamole , cilostazole Thienopyridine derivatives (ADP antagonists): Ticlodipine, clopidogrel Gp-IIb/IIIa receptor antagonists Abciximab, eptifibatide, tirofiban Others PGI2, daltroban, dazoxiben, clofibrate

Anticoagulant and antiplatelet are the two classes of antithrombotic drugs used to treat thrombosis. Some examples of anticoagulant drugs are heparin, warfarin, dabigatran, apixaban, and rivaroxaban while the two types of antiplatelets are aspirin and a P2Y12 inhibitor used in dual antiplatelet therapy (DAPT).

There are two classes of antithrombotic drugs: anticoagulants and antiplatelet drugs. Anticoagulants slow down clotting, thereby reducing fibrin formation and preventing clots from forming and growing. Antiplatelet agents prevent platelets from clumping and also prevent clots from forming and growing. Anticoagulant Drugs

antithrombotic drugs, including antiplatelet therapies and anticoagulants, are frequently used in patients with cardiovascular disease. This Series paper focuses on the pharmacological properties of the most commonly used oral antithrombotic drugs. Careful consideration of the effi cacy to safety ratio is

Antiplatelet agents are medicines that reduce the ability of platelets to stick together (called platelet aggregation) and inhibit the formation of blood clots. Antiplatelet agents play a major role in the treatment and prevention of myocardial infarction (heart attacks), stent thrombosis, and ischemic stroke (strokes caused by a blood clot).

Both acute and long-term oral antiplatelet therapies, targeting specific platelet activation pathways, have demonstrated significant short- and long-term benefits. The use of anticoagulants is currently largely confined to the acute setting, except in patients with a clear indication for long-term treatment, including atrial fibrillation or the presence of intraventricular thrombi.

Antithrombotic drugs, which include antiplatelet and anticoagulant therapies, prevent and treat many cardiovascular disorders and, as such, are some of the most commonly prescribed drugs worldwide. The first drugs designed to inhibit platelets or coagulation

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