Drug induced hypersensitivity syndrome

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❓ Drug induced hypersensitivity syndrome?

Drug-induced hypersensitivity syndrome (DIHS), also called drug rash with eosinophilia and systemic symptoms (DRESS), is a severe reaction usually characterized by fever, rash, and multiorgan failure, occurring 1-8 weeks after drug introduction.

❓ What is drug induced hypersensitivity syndrome?

Drug-induced hypersensitivity syndrome (DIHS), also called drug rash with eosinophilia and systemic symptoms (DRESS), is a severe reaction usually characterized by fever, rash, and multiorgan failure, occurring 1-8 weeks after drug introduction.

❓ Drug induced extrapyramidal syndrome?

Extrapyramidal symptoms, also called drug-induced movement disorders, describe the side effects caused by certain antipsychotic and other drugs. These side effects include: involuntary or uncontrollable movements. tremors.

Question from categories: drug induced dystonia drug induced eps drug induced parkinsonism drugs that cause tardive dyskinesia drug toxicity

❓ Drug induced long qt syndrome?

Drug-induced long QT syndrome. Letsas KP(1), Efremidis M, Filippatos GS, Sideris AM. Author information: (1)Second Department of Cardiology, Evangelismos General Hospital of Athens, Athens, Greece. [email protected] PMID: 17966685 [Indexed for MEDLINE] Publication Types: Review; MeSH terms. Action Potentials; Cytochrome P-450 CYP3A

❓ Drug induced ventricular tachycardia syndrome?

Drug-Induced Long QT Syndrome. Drug effects are the most common cause of acquired long QT syndrome. Although syncope occurring soon after the initiation of quinidine therapy was recognized as early as the 1920s, it was not until the advent of continuous electrocardiographic monitoring that “quinidine syncope” was recognized to be due to polymorphic ventricular tachycardia.

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Video answer: Hypersensitivity reactions| type 1, type 2, type 3 and type 4 hypersensitivity

Hypersensitivity reactions| type 1, type 2, type 3 and type 4 hypersensitivity

Video answer: Hypersensitivity basic concept

Hypersensitivity basic concept

Video answer: Introduction to hypersensitivity

Introduction to hypersensitivity

Video answer: Itching, शरीर में खुजली होने के कारण, लक्षण और उपाय, causes, symptoms, medicines for itching on skin

Itching, शरीर में खुजली होने के कारण, लक्षण और उपाय, causes, symptoms, medicines for itching on skin

Top 131474 questions from Drug induced hypersensitivity syndrome

We’ve collected for you 131474 similar questions from the «Drug induced hypersensitivity syndrome» category:

Drug induced depression?

Evidence was found linking corticosteroids, interferon-alpha, interleukin-2, gonadotropin-releasing hormone agonists, mefloquine, progestin-releasing implanted contraceptives and propranolol to the etiology of atypical depressive syndromes. Conclusions: A small number of drugs have been shown capable of inducing depressive symptoms.

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Drug induced depersonalization?

Drug-induced Depersonalization Disorder (DPD) is very common, and as stronger strains become more popular, Depersonalization from weed is becoming incredibly frequent. The most common situation is that you've had an bad experience or panic attack while on weed (or cannabis, LSD, ketamine etc) and now: I'm still high the next day

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Drug induced rhabdomyolysis?

Drug induced rhabdomyolysis Rhabdomyolysis is a clinical condition of potential life threatening destruction of skeletal muscle caused by diverse mechanisms including drugs and toxins. Given the fact that structurally not related compounds cause an identical phenotype pinpoints to common targets or pathways, responsible for ex …

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Drug induced acne?

Drug-induced acne. A variety of drugs may provoke acne, with drug-induced acne (DIA) often having some specific clinical and histopathologic features. DIA is characterized by a medical history of drug intake, sudden onset, and an unusual age of onset, with a monomorphous eruption of inflammatory papules or papulopustu ….

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Drug induced lupus?

The drugs most commonly connected with drug-induced lupus are: hydralazine (used to treat high blood pressure or hypertension) procainamide (used to treat irregular heart rhythms) isoniazid (used to treat tuberculosis)

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Drug induced scleroderma?

In recent years, drug-induced systemic sclerosis and scleroderma- like diseases have been reported in association with bleomycin, pentazocine, appetite suppressants, cocaine, I)-penicillamine, L-5-hydroxytryptophan and carbidopa (Table 1). Table 1. Drugs capable of inducing scleroderma and scleroderma-Iike lesions.

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Drug induced bipolar?

Drug induced bipolar disorder reflects the relationship between certain substances and how they impact brain chemistry. In some instances, stopping a prescription medication may spark mania and depressive episodes, as the

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Drug induced cholestasis?

Cholestasis caused by drugs is an important differential diagnosis in patients presenting with a biochemical cholestatic pattern. The extent of serologic tests and radiological imaging depends on the clinical context. The underlying condition of the patient and detailed information on drug use, results of rechallenge, and the documented ...

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Drug induced coma?

A drug-induced coma puts a person into a deep state of unconsciousness, which allows the brain to rest and thus decreases its swelling. The decrease in swelling can result in less pressure being put on the brain, which lessens the risk of damaging effects.

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Drug induced petechiae?

Drug-induced immune thrombocytopenia. Thrombocytopenia can have several causes, including the use of certain drugs. The mechanism behind drug-induced thrombocytopenia is either a decrease in platelet production (bone marrow toxicity) or an increased destruction (immune-mediated thrombocytopenia). In addition, pseudothrombocytopenia, an ….

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Drug induced paralysis?

Drug-induced paralysis in the mechanically ventilated neonate is prescribed primarily to control breathing and, secondarily, to favorably affect underlying pulmonary disease and associated complications. Although the control of breathing can be achieved, it is controversial when pulmonary disease is favorably influenced by paralysis.

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Drug induced psychosis?

Drug-induced psychosis can sometimes happen suddenly, or it can develop over a period of time. When a person takes too much of a certain drug, it can be hard for their body to process the toxins fast enough, resulting in paranoia, psychotic episodes, and drug-induced psychosis. Sometimes, the medications that someone may be taking to treat mental illnesses or other conditions may interact with substances and can trigger a serious mental reaction.

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Drug induced dyskinesia?

Drug induced dyskinesia is an involuntary movement disorder. Signs and symptoms include repetitive and irregular motions of the mouth, face, limbs and/or trunk. [1] Treatment with antipsychotic drugs and levodopa (commonly used to treat Parkinson disease ) are well recognized causes of drug-induced dyskinesia.

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Drug induced nightmares?

Drug-induced nightmares. Assessing causality with an event such as a nightmare is difficult because of the high incidence of nightmares in the healthy population. Using qualitative, quantitative, and possible pharmacologic mechanism criteria, it appears that sedative/hypnotics, beta-blockers, and amphetamines are the therap ….

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Drug induced dyspepsia?

Functional dyspepsia is the term used for patients when endoscopy and other diagnostic tests have ruled out organic pathology. The most common drugs that cause dyspepsia include aspirin and nonsteroidal anti-inflammatory drugs (NSAIDs), which can contribute to mucosal damage, ulceration, and bleeding complications.

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Drug induced anorexia?

Mechanisms of drug-induced anorexia Inhibition of dopamine and serotonin reuptake Increase of satiety-inducing hypothalamic neurotransmitters 8 Endogenous digoxin-like factor disruption Abnormal serum leptin levels Taste alternation Drug-induced nausea or vomiting

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Drug induced angioedema?

Angioedema (AE) is the end result of deep dermal, subcutaneous and/or submucosal swelling, and represents a major criterion in the definition of anaphylaxis. Drug-induced AE, like other cutaneous drug reactions, is most frequently elicited by betalactam

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Drug induced abnormalities?

Congenital abnormalities caused by medicinal substances or drugs of abuse given to or taken by the mother, or to which she is inadvertently exposed during the manufacture of such substances. The concept excludes abnormalities resulting from exposure to non-medicinal chemicals in the environment.

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Drug induced anemia?

Drug-induced anemia includes many kind of anemias with different mechanisms. Mechanisms of drug-induced anemia are divided into two groups, namely erythrocyte injury in peripheral blood and damage of erythroid progenitor cells or erythroblasts. Hemolytic anemias are included in the former and megaloblastic anemia, ringed sideroblastic anemia and ...

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Drug induced hallucinations?

Hallucinations / chemically induced* Humans Male Promethazine / adverse effects*

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Drug induced dementia?

Medication-induced dementia is a cognitive impairment of language, memory, and comprehension originating from or complicated by prescription or over-the-counter (OTC) medications. With the wide range of possible drugs that could contribute to the condition and the variance of symptoms, it is difficult to gather concrete evidence for the condition.

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Drug induced hyperthermia?

Diagnosis and treatment of drug-induced hyperthermia DIH is a hypermetabolic state caused by medications and other agents that alter neurotransmitter levels. The treatment of DIH syndromes includes supportive care and pharmacotherapy as appropriate.

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Drug induced hypnosis?

Requires a glass of water. Maybe it will contain a drug that leaves you suggestible... - Intended effect: Left suggestible through feeling drugged. • Downloa...

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Drug induced epilepsy?

Drug-induced seizures are a commonly encountered problem for physicians. In this article, drugs that cause seizures are discussed with regards to the incidence of seizures, associated clinical factors, risk factors, and special treatment considerations. This information should help physicians determ …

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Drug induced homicide?

A person commits drug-induced homicide when he or she unlawfully delivers a controlled substance to another, and any person’s death is caused by the injection, inhalation, absorption, or ingestion of any amount of that controlled substance. Learn more… Dealing Anguish

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Drug induced delirium?

Drugs can cause any of the three types of delirium: hyperactive, hypoactive, and mixed delirium. Both hyperactive and mixed delirium are commonly seen in cholinergic toxicity, alcohol intoxication, certain illicit drug (stimulant) intoxication, serotonin syndrome, alcohol and benzodiazepine withdrawal.

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Drug induced hives?

The most common type of drug reaction is hives, also known as urticaria. They are raised, swollen, red or flesh-colored bumps or welts that appear on the skin. They can take on many shapes and can be very itchy. They usually develop in groups and may cover large areas of skin.

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Drug induced esophagitis?

Drug or pill-induced esophagitis is esophageal mucosal injury caused by the medications and usually refers to a direct toxic effect on esophageal mucosa by the culprit medication. Common symptoms include retrosternal pain, dysphagia, or odynophagia.

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Drug induced fever?

Drug-induced fever is most commonly the result of a hypersensitivity reaction and its characteristics resemble those of an allergic reaction. The fever most commonly occurs after 7 to 10 days of drug administration, persists as long as the drug is continued, disappears soon after stopping the drug, and will rapidly reappear if the drug is restarted.

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Drug induced parkinsonism?

Drug-induced parkinsonism (DIP) is the second-most-common etiology of parkinsonism in the elderly after Parkinson's disease (PD). Many patients with DIP may be misdiagnosed with PD because the clinical features of these two conditions are indistinguishable.

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Drug induced neutropenia?

Drug-induced neutropenia is a potentially serious and life-threatening adverse event that may occur secondary to therapy with a variety of agents. Cytotoxic chemotherapy can cause a predictable and dose-related decrease in neutrophil count.

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Drug induced schizophrenia?

Other drug-induced schizophrenia can be triggered by high doses of stimulants, such as cocaine, amphetamines, and methamphetamine. Not as well known is that some prescription medications can also cause signs of psychosis. These include: Allergy drugs; Anticonvulsants; Corticosteroids; Muscle relaxants; Heart medications; Analgesics; Chemo drugs

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Drug induced migraine?

Medication overuse headaches or rebound headaches are caused by regular, long-term use of medication to treat headaches, such as migraines. Pain relievers offer relief for occasional headaches. But if you take them more than a couple of days a week, they may trigger medication overuse headaches.

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Drug induced pancreatitis?

Class II medications (medications implicated in more than 10 cases of acute pancreatitis): rifampin, lamivudine, octreotide, carbamazepine, acetaminophen, phenformin, interferon alfa-2b, enalapril, hydrochlorothiazide, cisplatin, erythromycin, and cyclopenthiazide. Class III medications (all medications reported to be associated with pancreatitis). Of the top 100 most frequently prescribed medications in the United States, 44 have been implicated in AP, 14 of them fall into either Class I or ...

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Drug induced narcolepsy?

There is a sleeping medication that was recently approved, the function of which is (theorized to be) inducing narcolepsy for a controlled period of time. It does this by blocking Orexin (hypocretin) which is a neurotransmitter believed to promote wakefulness.

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Drug induced paranoia?

Substances that can cause paranoia during intoxication or withdrawal include: Cocaine Methamphetamine Other Amphetamines LSD Bath Salts Hallucinogens Marijuana Alcohol

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Drug induced thrombocytopenia?

Drug-induced thrombocytopenia (DIT) is a relatively common clinical disorder. It is imperative to provide rapid identification and removal of the offending agent before clinically significant bleeding or, in the case of heparin, thrombosis occurs.

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Drug induced toxicity?

Drug-induced nephrotoxicity. Acute kidney injury is a very common diagnosis, present in up to 60% of critical patients, and its third main cause is drug toxicity. Nephrotoxicity can be defined as any renal injury caused directly or indirectly by medications, with acute renal failure, tubulopathies, and glomerulopathies as commo ….

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Drug induced pancytopenia?

Medications that can affect bone marrow function include chloramphenicol, chemotherapy drugs, thiazide diuretics, anti-epileptic drugs, colchicine, azathioprine, and non-steroidal anti-inflammatory drugs (NSAIDs). The list here covers just some of the potential disease-related pancytopenia causes.

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Drug induced thyrotoxicosis?

Background: Drug-induced thyrotoxicosis is not uncommon. It may worsen life-threatening arrhythmias and may be refractory to medical treatment. Near-total thyroidectomy presents a valid alternative to medical therapy and should be considered early in the management of the disease.

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Drug induced tremor?

Drug-induced tremor is a simple nervous system and muscle response to certain medicines. Drugs that can cause tremor include the following: Cancer medicines such as thalidomide and cytarabine; Seizure medicines such as valproic acid (Depakote) and sodium valproate (Depakene) Asthma medicines such as theophylline and albuterol

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Drug induced vasculitis?

Drug-induced vasculitis is an inflammation of blood vessels caused by the use of various pharmaceutical agents. Vasculitis causes changes in the walls of blood vessels, including thickening, weakening, narrowing and scarring. Inflammation can be short-term (acute) or long-term (chronic) and can be so severe that the tissues and organs supplied by the affected vessels do not get enough blood.

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Drug induced vomiting?

Nausea and vomiting, common side effects of drugs, usually occur early in the course of pharmacologic therapy. Often, the symptoms will disappear with continued use. In some instances, concurrent administration of antiemetics may be needed to prevent dehydration and electrolyte imbalances.

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Drug induced sle?

Drug-induced lupus erythematosus is an autoimmune disorder caused by chronic use of certain drugs. These drugs cause an autoimmune response (the body attacks its own cells) producing symptoms similar to those of systemic lupus erythematosus (SLE).

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Drug induced ileus?

Drug-induced ileus is often seen with anticholinergic drugs, opiates, and calcium antagonists. 1, 2, 3 In its mild form, it can cause constipation that resolves with drug cessation. In more severe cases, adynamic ileus can develop with fecal loading that may persist for longer periods and require intervention to relieve it.

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Drug induced rash?

Drug-induced rash is the most commonly reported drug reaction and occurs in a dizzying array of presentations. Changes in lean and fat body tissue, gastrointestinal acid and mucosal permeability, cardiac output, and renal and hepatic metabolism can affect drug absorption, distribution, metabolism, and elimination.

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Thrombocytopenia - drug induced?

DefinitionThrombocytopenia is any disorder in which there are not enough platelets. Platelets are cells in the blood that help the blood clot. A low platelet count makes bleeding more likely.When drugs or medications are the causes of a low platelet count, it is called drug-induced thrombocytopenia.See also: ThrombocytopeniaAlternative NamesDrug-induced thrombocytopeniaCauses, incidence, and risk factorsDrug-induced thrombocytopenia occurs when certain drugs or medications destroy platelets (the cells that help blood clot) or interfere with the body's ability to make enough of them.There are two types of drug-induced thrombocytopenia:

  • Immune
  • Nonimmune
If a drug causes your body to produce antibodies, which seek and destroy your platelets, the condition is called drug-induced immune thrombocytopenia. Heparin, a blood thinner, is probably the most common cause of drug-induced immune thrombocytopenia.If a medicine prevents your bone marrow from making enough platelets, the condition is called drug-induced nonimmunethrombocytopenia. Chemotherapy drugs and a seizure medication called valproic acid may lead to this problem.Other drugs that cause drug-induced thrombocytopenia include:
  • Diabetes drugs taken by mouth
  • Nonsteroidal anti-inflammatory drugs (NSAIDs)
  • Penicillin
  • Quinidine
  • Quinine
  • Ranitidine
  • Some drugs used to treat arthritis conditions
  • Sulfonamides
  • Water pills (diuretics)
SymptomsDecreased platelets may cause:
  • Bleeding when you brush your teeth
  • Easy bruising
  • Pinpoint red spots on the skin (petechiae)
  • Other abnormal bleeding
Signs and testsSee: ThrombocytopeniaTreatmentThe first step in treating this type of low platelet count is to stop using the drug that may be causing the problem.For people who have life-threatening bleeding, treatments may include:
  • Immunoglobulin therapy (IVIG) given through a vein
  • Plasma exchange (plasmapheresis)
  • Platelet transfusions
ComplicationsBleeding can be life threatening if it occurs in the brain or other organs.A pregnant woman who has antibodies to platelets may pass the antibodies to the baby in the womb.Calling your health care providerCall your healthcare provider if you have unexplained bleeding or bruising.ReferencesVisentin GP, Liu CY. Drug-induced thrombocytopenia. Hematol Oncol Clin North Am. 2007;21:685-696.Warkentin TE. Thrombocytopenia due to platelet destruction and hypersplenism. In: Hoffman R, Benz Jr. EJ, Shattil SJ, Furie B, Silberstein LE, eds. Hematology: Basic Principles and Practice. 5th ed. Philadelphia, Pa: Elsevier Churchill Livingstone;2008:chap 140.

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Drug induced tinnitus?

Specific drugs and tinnitus Aspirin. Aspirin in large doses has long been recognised as being able to cause tinnitus and indeed researchers use this... Quinine. Quinine and some of the other anti-malarial drugs can occasionally cause damage to the ear when given in high... Aminoglycoside ...

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Drug induced coagulopathy?

Neuroleptic drug-induced coagulopathy: mechanism of reaction and duration of effect. Zengotita HE, Holt RJ. Patients (N = 32) with documented phenothiazine-induced reductions in platelet levels were evaluated after drug substitution with haloperidol; 28 (88%) patients had normal platelet levels after 1 year of treatment with haloperidol.

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Drug-induced diarrhea?

DefinitionDrug-induced diarrhea is loose, watery stools caused by certain medications.See also: DiarrheaAlternative NamesDiarrhea associated with medicationsCauses, incidence, and risk factorsNearly all medications may cause diarrhea as a side effect. Some medications, however, are more prone to cause diarrhea than others. For example:

  • Laxatives can and are meant to produce diarrhea by drawing water into the gut or increasing the muscle contractions of the intestine. However, taking too much of a laxative, or taking a laxative without being aware of it can cause diarrhea that is a problem.
  • Antibiotics can produce diarrhea by destroying the bacteria of the gut. In some cases, antibiotics can allow a type of bacteria called Clostridium difficile to grow in excess. This can lead to infection and produce a severe, watery form of diarrhea called pseudomembranous colitis.
  • Other drugs may be directly toxic to the digestive tract. Chemotherapy medicines for cancer, or medications that suppress the immune system (such as mycophenolate) are a common cause of diarrhea.
  • Some herbal teas contain senna or other "natural" laxatives that can cause diarrhea.
PreventionTo prevent diarrhea related to antibiotic use, talk to your doctor about taking supplements containing beneficial bacteria (probiotics). Continue taking these supplements for a few days after you finish taking the course of antibiotics.ReferencesSemrad CE, Powell DW. Approach to the patient with diarrhea and malabsorption. In: Goldman L, Ausiello D, eds.Cecil Medicine. 23rd ed. Philadelphia, Pa: Saunders Elsevier;2007:chap 143.

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