What drugs can damage the liver cells?

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Ansley Schmidt asked a question: What drugs can damage the liver cells?
Asked By: Ansley Schmidt
Date created: Sat, Jun 19, 2021 10:36 AM
Date updated: Fri, Jan 14, 2022 10:59 PM

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Those who are looking for an answer to the question «What drugs can damage the liver cells?» often ask the following questions:

⚕ Can antibiotics damage the liver cells?

The liver also produces a protein called albumin which helps transport antibiotics and important immune molecules around the blood to infection sites.

⚕ What drugs damage liver?

  • These may range from common drugs like acetaminophen (fever remedy) that may lead to liver failure in overdoses. Some drugs that lower cholesterol like Statins and Niacin also damage the liver. Other liver damaging drugs include nitrofurantoin, tetracycline, isoniazid (antibiotics) or Methotrexate (anti-cancer drug).

⚕ What drugs damage the liver?

Acetaminophen is known to cause liver damage by producing a toxic metabolite in the body that accumulates over time and causes a change in the structure of the liver, which lowers its ability to work normally. Other pain medicines that are commonly associated with liver injury include Advil (ibuprofen), Voltaren (diclofenac), and sulindac.

9 other answers

Common Medications That Can Cause Liver Damage. The best known medication that can damage the liver is acetaminophen, also known as Tylenol®. This medication is widely available without prescription and is present in many of the cold and flu remedies sold in drugstores as well as in prescription pain medications.

Acetaminophen is known to cause liver damage by producing a toxic metabolite in the body that accumulates over time and causes a change in the structure of the liver, which lowers its ability to work normally. Other pain medicines that are commonly associated with liver injury include Advil (ibuprofen), Voltaren (diclofenac), and sulindac.

Some antidepressants can damage your liver over time, including monoamine oxidase (MAO) inhibitors, tricyclic or tetracyclic antidepressants, bupropion, duloxetine and agomelatine. Antidepressant drugs with a lower risk of liver damage include citalopram, escitalopram, paroxetine and fluvoxamine. 5

Acetylcysteine: If you think an acetaminophen overdose caused your liver disease, quickly go to the hospital to get this drug. It can help prevent liver damage.

This prescription medication has been linked to drug-induced liver damage and disease. Patients who take amiodarone are advised to undergo tests for ALT and AST to verify any spikes in transaminase elevations.

Any NSAID (non-steroidal anti-inflammatory drug) can cause liver injury, although it’s very rare. This class of medications includes popular drugs like ibuprofen and naproxen . But when it comes to liver injury, diclofenac is the NSAID with the highest risk.

Some drugs, such as statins (used to treat high cholesterol), can increase the levels of liver enzymes and cause liver damage (usually minor) but no symptoms. However, doctors may continue to prescribe statins for people with chronic liver diseases (for example, nonalcoholic fatty liver disease [NAFLD], nonalcoholic steatohepatitis [NASH], and NASH cirrhosis ), because:

For example, an overdose of acetaminophen (Tylenol) can destroy half of a person's liver cells in less than a week. Barring complications, the liver can repair itself completely and, within a month, the patient will show no signs of damage. However, sometimes the liver gets overwhelmed and can't repair itself completely, especially if it's still under attack from a virus, drug, or alcohol. Scar tissue develops, which becomes difficult to reverse, and can lead to cirrhosis.

There are three types of liver toxicity; dose-dependent toxicity, idiosyncratic toxicity, and drug allergy. Drugs that cause dose-dependent toxicity can cause liver disease in most people if enough of the drug is taken. The most important example of dose-dependent toxicity is acetaminophen (Tylenol) overdose (discussed later in this article.).

Your Answer

We've handpicked 20 related questions for you, similar to «What drugs can damage the liver cells?» so you can surely find the answer!

What prescription drugs can damage liver?

The 10 Worst Medications for Your Liver

  • 1) Acetaminophen (Tylenol) ...
  • 2) Amoxicillin/clavulanate (Augmentin) ...
  • 3) Diclofenac (Voltaren, Cambia) ...
  • 4) Amiodarone (Cordarone, Pacerone) ...
  • 5) Allopurinol (Zyloprim) ...
  • 6) Anti-seizure medications…
  • 7) Isoniazid…
  • 8) Azathioprine (Imuran)
What prescription drugs cause liver damage?

If you don’t want your liver damaged by medication, check out this list of the most common prescription drugs that may cause liver malfunction or damage: Amoxicillin As one of the most commonly prescribed antibiotics, amoxicillin is designed to address bacterial infection caused by:

What prescription drugs damage the liver?

It falls under the category of non-steroidal anti-inflammatory drugs (NSAIDs) and carries a number of side effects. When taken in full dosage in a continuous treatment program, diclofenac may cause mildly elevated transaminase, which is an indicator of damage in the liver.

Can drugs damage your liver?

Chronic use of some drugs, such as heroin, inhalants, and steroids (appearance- and performance-enhancing drugs), may lead to significant damage to the liver. This damage can be worse when these drugs are combined with alcohol or other drugs.

Do drugs damage your liver?

Health Consequences of Drug Misuse. Liver Damage. Chronic use of some drugs, such as heroin, inhalants, and steroids (appearance- and performance-enhancing drugs), may lead to significant damage to the liver. This damage can be worse when these drugs are combined with alcohol or other drugs.

Which drugs cause liver damage?

The 10 Worst Medications for Your Liver

  • 1) Acetaminophen (Tylenol) ...
  • 2) Amoxicillin/clavulanate (Augmentin) ...
  • 3) Diclofenac (Voltaren, Cambia) ...
  • 4) Amiodarone (Cordarone, Pacerone) ...
  • 5) Allopurinol (Zyloprim) ...
  • 6) Anti-seizure medications…
  • 7) Isoniazid…
  • 8) Azathioprine (Imuran)
What drugs can liver break down cells?

In the case of acetaminophen, alcohol use leads to accumulation in the liver of a toxic byproduct of acetaminophen that can kill the liver cells. People who drink alcohol regularly should not take acetaminophen or take it in small doses if at all.

What chemo drugs cause liver damage pictures?

Enzymes speed up chemical reactions in the body. In the liver, they help remove toxins, produce bile and break down nutrients in food, according to the Cleveland Clinic. Higher-than-normal liver enzymes might be a sign of liver inflammation, a response to the extra work the organ does to metabolize chemo drugs while you're undergoing treatment.

What chemo drugs cause liver damage symptoms?

Nonsteroidal anti-inflammatory drugs (NSAIDs) Aspirin, ibuprofen, and naproxen sodium can cause toxic liver disease if you take too much of the drug or take it with alcohol.

What drugs can damage the liver naturally?

“There is increasing evidence that complementary and alternative medicines such as supplements and herbs can cause liver damage. These include kava, Comfrey, mistletoe and others ,” says Lauren Aleksunes, PharmD, PhD, associate professor of pharmacology and toxicology at the Ernest Mario School of Pharmacy at Rutgers University, and resident scientist at the Environmental and Occupational Health Sciences Institute.

What drugs cause damage to the liver?

The 10 Worst Medications for Your Liver

  • 1) Acetaminophen (Tylenol) ...
  • 2) Amoxicillin/clavulanate (Augmentin) ...
  • 3) Diclofenac (Voltaren, Cambia) ...
  • 4) Amiodarone (Cordarone, Pacerone) ...
  • 5) Allopurinol (Zyloprim) ...
  • 6) Anti-seizure medications…
  • 7) Isoniazid…
  • 8) Azathioprine (Imuran)
What drugs cause liver damage are called?

Toxic liver disease is damage to your liver.It’s also called hepatotoxicity or toxic hepatitis.It can cause serious symptoms or liver damage if you don’t get help. Medications, herbal ...

What drugs cause liver damage besides alcohol?

According to the Canadian Liver Foundation (CLF), something like liver disease is often associated with drugs and alcohol, but in fact, liver disease (which has over 100 known forms) can be caused ...

What drugs cause liver damage in dermatopolymyositis?

Can cause liver damage; used in higher doses to treat cancer. cyclosporine (Neoral, Sandimmune) Keeps T cells from stimulating production of more T cells and B cells (“upstream” of azathioprine and methotrexate action).

What drugs cause liver damage in dogs?

Many drugs have been suspected of causing hepatic injury in dogs and cats. Most adverse hepatic drug reactions are associated with acute hepatic injury. However, some drugs, most notably Phenobarbital, lomustine, oxibendazole/DEC (and possibly carprofen and amiodarone) may be a cause of chronic hepatic injury.

What drugs & supplements can damage the liver?

Acetaminophen is known to cause liver damage by producing a toxic metabolite in the body that accumulates over time and causes a change in the structure of the liver, which lowers its ability to work normally. Other pain medicines that are commonly associated with liver injury include Advil (ibuprofen), Voltaren (diclofenac), and sulindac.

What illegal drugs cause liver damage pictures?

Liver Damage. Chronic use of some drugs, such as heroin, inhalants, and steroids (appearance- and performance-enhancing drugs), may lead to significant damage to the liver. This damage can be worse when these drugs are combined with alcohol or other drugs.

What illegal drugs damage your liver symptoms?

Chronic use of some drugs, such as heroin, inhalants, and steroids (appearance- and performance-enhancing drugs), may lead to significant damage to the liver. This …

What illegal drugs damage your liver system?

Drugs that can cause liver damage: DXM Heroin Inhalants Steroids (appearance- and performance-enhancing drugs)

What illegal drugs damage your liver without?

Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. Data sources include IBM Watson Micromedex (updated 31 Aug 2021), Cerner Multum™ (updated 1 Sep 2021), ASHP (updated 30 Aug 2021 ...