What is drug drug interaction?

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Video answer: Drug-drug interactions (memorable psychopharmacology)

Drug-drug interactions (memorable psychopharmacology)

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A drug interaction is a change in the action or side effects of a drug caused by concomitant administration with a food, beverage, supplement, or another drug. A cause of a drug interaction involves one drug which alters the pharmacokinetics of another medical drug.

Drug-drug interaction (DDI) can occur when two or more drugs are co-administered to a patient. It can lead to changed systemic exposure, resulting in variations in drug response of the co-administered drugs. DDIs generally occur due to inhibition of the metabolism for one drug by the other.

Drug Interactions

Drug-drug interaction (DDI) can occur when two or more drugs are co-administered to a patient. It can lead to changed systemic exposure, resulting in variations in drug response of the co-administered drugs. DDIs generally occur due to inhibition of the metabolism for one drug by the other.

A drug interaction is a reaction between two (or more) drugs or between a drug and a food, beverage, or supplement. Taking a drug while having certain medical conditions can also cause a drug interaction. For example, taking a nasal decongestant if you have high blood pressure may cause an unwanted reaction.

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❓ Drug-drug interaction studies: what is a drug interaction?

Commonly referred to as drug-drug interactions, this phenomenon usually occurs when a drug affects the expression or function of a metabolic enzyme or transporter.

Question from categories: potential drug adverse drug drug development vitro drug

❓ What is drug interaction?

A drug interaction is a reaction between two (or more) drugs or between a drug and a food, beverage, or supplement. Taking a drug while having certain medical conditions can also cause a drug interaction. For example, taking a nasal decongestant if you have high blood pressure may cause an unwanted reaction.

❓ Additive drug interaction?

When two drugs are used together, their effects can be additive (the result is what you expect when you add together the effect of each drug taken independently), synergistic (combining the drugs leads to a larger effect than expected), or antagonistic (combining the drugs leads to a smaller effect than expected).

Question from categories: drug interactions list of synergistic drug combinations drug drug interaction list synergistic effect of drugs examples types of drug interactions and examples

Video answer: Drug interactions

Drug interactions

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A drug interaction is a reaction between two (or more) drugs or between a drug and a food, beverage, or supplement. Taking a drug while having certain medical conditions can also cause a drug interaction. For example, taking a nasal decongestant if you have high blood pressure may cause an unwanted reaction.

Drug-drug interactions occur when two or more drugs react with each other. This ...

Commonly referred to as drug-drug interactions, this phenomenon usually occurs when a drug affects the expression or function of a metabolic enzyme or transporter. Since metabolism is the primary mechanism for elimination of most drugs, changes in the enzymes responsible for drug metabolism can lead to undesirable increases (or decreases) in the plasma concentration of drugs.

drug-drug interaction: a modification of the effect of a drug when administered with another drug. The effect may be an increase or a decrease in the action of either substance, or it may be an adverse effect that is not normally associated with either drug. The particular interaction may be the result of a chemical-physical incompatibility of ...

Drug-Drug Interaction DDI is defined as “The pharmacologic or clinical response to the administration of a drug combination different from that anticipated from the known effect of the two agents when given alone”. From: Pulmonary Pharmacology & Therapeutics, 2014

Drug–drug interactions (DDIs) occur when one drug interferes with the pharmacological activity of another. These interactions can result in decreased effectiveness and/or increased toxicity. Additionally they may result in the development of ADRs, morbidity, hospitalizations and death.

Drug interactions that cause important changes in the action of a drug are of the greatest concern. Drug interactions are complex and chiefly unpredictable. A known interaction may not occur in every individual.

What are drug interactions? Drug-drug interactions - These are the most common type of drug interaction. The more medications you take, the greater... Drug-food/beverage interactions - You have probably seen the stickers on your prescription bottle to “ avoid grapefruit... Drug-disease interactions ...

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We've handpicked 24 related questions for you, similar to «What is drug drug interaction?» so you can surely find the answer!

What does drug moderate interaction mean?

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Major: The interaction may be life-threatening or cause permanent damage. Moderate: The patient's condition may deteriorate due to the interaction, requiring additional care or extended hospitalization. Minor: An interaction that is bothersome, but otherwise not medically detrimental.

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What does moderate drug interaction mean?

Moderate drug-drug interactions may result in exacerbation of the disease of the patient and/or a change in the therapy. The severe drug-drug interactions are life threatening and/or they require medical treatment or an intervention to minimize or to prevent the severe adverse effects.

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What is drug interaction and types?

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Drug-drug interactions can involve prescription or nonprescription (over-the-counter) drugs. Types of drug-drug interactions include duplication, opposition (antagonism), and alteration of what the body does to one or both drugs.

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What is meaning of drug interaction?

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IN-teh-RAK-shun) A change in the way a drug acts in the body when taken with certain other drugs, herbals, or foods, or when taken with certain medical conditions. Drug interactions may cause the drug to be more or less effective, or cause effects on the body that are not expected.

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Drug interaction or adverse drug reaction?

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The World Health Organization defines an adverse drug reaction as any noxious, unintended and unwanted response to a drug that occurs at doses normally used for treatment, prophylaxis or diagnosis.

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Video answer: 134a drug interactions pharmacology basics

134a drug interactions pharmacology basics

Can drug interaction cause convulsions?

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Seizures are a common complication of drug intoxication, and up to 9% of status epilepticus cases are caused by a drug or poison. While the specific drugs associated with drug‐induced seizures may vary by geography and change over time, common reported causes include antidepressants, stimulants and antihistamines.

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Cipro and ibuprofen drug interaction?

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Ciprofloxacin may rarely cause central nervous system side effects such as tremors, involuntary muscle movements, anxiety, confusion, depression, hallucinations or seizures, and combining it with other medications that can also affect the central nervous system such as ibuprofen may increase that risk.

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Video answer: Antimicrobial drug interactions -- tiffany ward, pharmd

Antimicrobial drug interactions -- tiffany ward, pharmd

Drug interaction cymbalta and klonopin?

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Interactions between your drugs

Using clonazePAM together with DULoxetine may increase side effects such as dizziness, drowsiness, confusion, and difficulty concentrating. Some people, especially the elderly, may also experience impairment in thinking, judgment, and motor coordination.

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Fluoxetine and metoprolol drug interaction?

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Using metoprolol together with FLUoxetine may increase the effects of metoprolol. Contact your doctor if you experience uneven heartbeats, shortness of breath, bluish-colored fingernails, dizziness, weakness, fainting, or seizure (convulsions).

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Naproxen and ibuprofen drug interaction?

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Using ibuprofen together with naproxen is generally not recommended. Combining these medications may increase the risk of side effects in the gastrointestinal tract such as inflammation, bleeding, ulceration, and rarely, perforation.

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Video answer: Basics of drug-receptor interaction part 1

Basics of drug-receptor interaction part 1

Xanax and benadryl drug interaction?

Using ALPRAZolam together with diphenhydrAMINE may increase side effects such as dizziness, drowsiness, confusion, and difficulty concentrating. Some people, especially the elderly, may also experience impairment in thinking, judgment, and motor coordination.

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What does drug interaction mean in pharmacology?

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Drug interactions occur when one drug alters the pharmacological effect of another drug. The pharmacological effect of one or both drugs may be increased or decreased, or a new and unanticipated adverse effect may be produced.

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What does drug interaction mean in science?

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Drug interactions occur when one drug alters the pharmacological effect of another drug. The pharmacological effect of one or both drugs may be increased or decreased, or a new and unanticipated adverse effect may be produced.

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What does the phrase drug interaction mean?

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IN-teh-RAK-shun) A change in the way a drug acts in the body when taken with certain other drugs, herbals, or foods, or when taken with certain medical conditions. Drug interactions may cause the drug to be more or less effective, or cause effects on the body that are not expected.

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What can cause a nutrient or drug interaction?

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Nutrient supplements themselves can result in drug-nutrient interactions. In excessive amounts, vitamins and minerals act like drugs instead of nutrients. Nutrients in excessive amounts may interact with other nutrients or may even be toxic. Large amounts of zinc can interfere with copper and iron absorption.

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What does an exothermic drug receptor interaction mean?

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Drug Interaction with Receptor Site. A neurotransmitter has a specific shape to fit into a receptor site and cause a pharmacological response such as a nerve impulse being sent. The neurotransmitter is similar to a substrate in an enzyme interaction. After attachment to a receptor site, a drug may either initiate a response or prevent a response from occurring.

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What is an example of a drug interaction?

Drug interactions occur on pharmacodynamic and pharmacokinetic levels. Examples of pharmacodynamic interactions are simultaneous administration of a NSAID and phenprocoumon (additive interaction), or of aspirin and ibuprofen (antagonistic interaction).

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What is the principle of drug receptor interaction?

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Molecules (eg, drugs, hormones, neurotransmitters) that bind to a receptor are called ligands. The binding can be specific and reversible. A ligand may activate or inactivate a receptor; activation may increase or decrease a particular cell function. Each ligand may interact with multiple receptor subtypes.

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Video answer: Drug–drug interactions: what remains relevant in hcv treatment? david back, liverpool, uk

Drug–drug interactions: what remains relevant in hcv treatment? david back, liverpool, uk

Can a drug interaction cause edema?

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The most commonly used drugs which can cause edema are: • calcium channel blockers e.g. amlodipine • nonsteroidal anti-inflammatory drugs (NSAIDs) e.g. ibuprofen • corticosteroids e.g. prednisolone • hormones and related compounds e.g. tamoxifen Calcium channel blockers (CCBs) These are probably the medications most ...

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What is the most common type of drug interaction?

pharmacokinetic – defined as an alteration in the absorption, distribution, metabolism or excretion of one drug by another. This is the most common type of drug interaction. pharmacodynamic – where the drug affects the action or effect of the other drug.

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Video answer: Drug interaction in pharmacology

Drug interaction in pharmacology